Explore/agent app/CVEvolve: Autonomous Algorithm Discovery for Unstructured Scientific Data Processing
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Ming Du, Xiangyu Yin, Yanqi Luo, Dishant Beniwal, Songyuan Tang, Hemant Sharma, Mathew J. Cherukara/CVEvolve: Autonomous Algorithm Discovery for Unstructured Scientific Data ProcessingUnknown

Scientific data processing often requires task-specific algorithms or AI models, creating a barrier for domain scientists who need to analyze their data but may not have extensive computing or image-processing expertise. This barrier is especially pronounced when data are noisy, have a high dynamic range, are sparsely labeled, or are only loosely specified. We introduce CVEvolve, an autonomous agentic harness with a zero-code interface for scientific data-processing algorithm discovery. CVEvolve combines a multi-round search strategy with tools for code execution, evaluation implementation, history management, holdout testing, and optional inspection of scientific data and visual outputs. The search alternates between discovery and improvement actions, and uses lineage-aware stochastic candidate sampling to balance exploration and exploitation. We demonstrate CVEvolve on x-ray fluorescence microscopy image registration, Bragg peak detection, and high-energy diffraction microscopy image segmentation. Across these tasks, CVEvolve discovers algorithms that improve over baseline methods, while holdout test tracking helps identify candidates that generalize better than later over-optimized alternatives. These results show that zero-code, autonomous LLM-powered algorithm development can help domain scientists turn unstructured scientific image data into practical algorithms and downstream scientific discoveries.

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2026-07-262026-08-27
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